One of the mysteries of the English language finally explained.
A substance secreted like a hormone but having the effect of inhibiting a physiological process.
- ‘Regression of generalized leukaemia in rat is induced by the granulocytic chalone.’
- ‘In addition, European researchers provided evidence for endogenous growth inhibitory substances, called chalones, in glands and tissues.’
- ‘A reaction based on chalones cannot explain the re-transformation of the tumour into normal skin cells.’
- ‘This volume is a series of up-to-date articles on chalones.’
Early 20th century: from Greek khalōn ‘slackening’, present participle of khalaein, on the pattern of hormone.
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