Definition of chalone in English:

chalone

noun

Biochemistry
  • A substance secreted like a hormone but having the effect of inhibiting a physiological process.

    • ‘In addition, European researchers provided evidence for endogenous growth inhibitory substances, called chalones, in glands and tissues.’
    • ‘Regression of generalized leukaemia in rat is induced by the granulocytic chalone.’
    • ‘A reaction based on chalones cannot explain the re-transformation of the tumour into normal skin cells.’
    • ‘This volume is a series of up-to-date articles on chalones.’

Origin

Early 20th century: from Greek khalōn slackening, present participle of khalaein, on the pattern of hormone.

Pronunciation:

chalone

/ˈkaləʊn/