One of the mysteries of the English language finally explained.
Originally: designating the cingulate sulcus, which lies between the cingulate gyrus and the superior frontal gyrus on the medial surface of the brain. In later use also: of or relating to this sulcus; specifically designating a large branch of the anterior cerebral artery which follows the course of this sulcus.
Mid 19th century; earliest use found in Thomas Huxley (1825–1895), biologist and science educationist. From callos- + -o- + marginal.
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