Definition of binding site in English:

binding site


  • A location on a macromolecule or cellular structure at which chemical interaction with a specific active substance takes place.

    • ‘The same pauses and jumps were observed in unzipping fork dynamics and were attributed to protein binding sites.’
    • ‘Alternatively, it could have been due to another binding site within the channel.’
    • ‘The mutations caused a different pattern of cofactor interaction within the enzyme binding site.’
    • ‘However, many of these binding sites span two nucleic acid molecules.’
    • ‘In addition to this recognition site, there is often a second downstream binding site with less similarity to the operator sequence.’