Definition of antiretroviral in English:



  • Denoting or relating to a class of drugs which inhibit the activity of retroviruses such as HIV.

    • ‘Patients who were prescribed antiretroviral therapy were seen four weeks after starting treatment, and then every 12 weeks.’
    • ‘Immune reconstitution disease is a well known complication of highly active antiretroviral therapy.’
    • ‘Advances in antiretroviral drug therapies now make it possible to treat the disease.’
    • ‘Long term probability of detection of HIV - 1 drug resistance after starting antiretroviral therapy in routine clinical practice.’
    • ‘Furthermore, antiretroviral therapy may be less effective or less well tolerated in some patients who present with more advanced disease.’
    • ‘Should someone who has just been found to have a primary infection with HIV be treated with highly active antiretroviral therapy?’
    • ‘In two of the 10 cases, resistance against two of the three available classes of antiretroviral agents was identified.’
    • ‘The first choice of regimen of highly active antiretroviral therapy is crucial.’
    • ‘Failure to identify primary HIV infection denies patients the opportunity of receiving potent antiretroviral therapy at the time of HIV seroconversion.’
    • ‘Clinicians consider immune reconstitution syndrome whenever the patient on antiretroviral therapy deteriorates after initial response.’
    • ‘The prevalence of adverse events related to these drugs may rise as the use of antiretroviral therapy increases.’
    • ‘Other explanations include the possibility that three or four drug antiretroviral therapy is not started early enough in infants.’
    • ‘Nevertheless, it is not advisable to begin both antiretroviral therapy and combination chemotherapy for tuberculosis at nearly the same time.’
    • ‘It is likely that future recommendations on mode of delivery will vary depending on the patient's viral load and prior antiretroviral therapy.’
    • ‘An estimated six million people currently living with HIV or AIDS do not have access to care, including antiretroviral therapy.’
    • ‘There are three main classes of antiretroviral drug.’
    • ‘Included are recommendations about when to begin antiretroviral therapy, what therapy to use, how to monitor the therapy and when to change therapy.’
    • ‘Systematic review and meta-analysis of evidence for increasing numbers of drugs in antiretroviral combination therapy’
    • ‘Three classes of antiretroviral drugs are currently used in combination for the treatment of HIV infection, which target the activity of two viral enzymes.’
    • ‘The new Guidelines provide practitioners with a list of suggested combination regimens for the initiation of antiretroviral therapy.’


  • An antiretroviral drug.

    • ‘The standard procedure and test for quality specification of antituberculosis drugs, antiretrovirals and antimalarials have been incorporated.’
    • ‘Put him on antiretrovirals, his HIV in his plasma went away completely, and his renal disease not only stabilised, but got better.’
    • ‘In Brazil, Thailand and India there are companies that can produce generic versions of many drugs including antiretrovirals.’
    • ‘The plan is to ease the WTO's rules on patents so that drugs such as antiretrovirals for combating HIV infection and AIDS could be produced to meet urgent public health needs in the world's poorer countries.’
    • ‘This proportion is only an imperfect surrogate of the presence of mutations giving rise to resistance to antiretrovirals.’
    • ‘Under the scheme WHO has set a global target of getting three million people with HIV or AIDS in developing and middle income countries treated with antiretrovirals by 2005.’
    • ‘The uncontrolled use of antiretrovirals in these areas is therefore of particular concern, as it may result in the emergence and widespread circulation of multi-drug resistant strains generated through recombination.’
    • ‘Botswana has also been successful in getting funds from the Bill and Melinda Gates Foundation, the Harvard School of Public Health, and Merck, one of the drug companies making antiretrovirals.’
    • ‘Boxes of medicines, varying from children's syrup to Viagra and antiretrovirals, were found in the warehouse.’
    • ‘Drug development, especially for antiretrovirals, is an uncertain and risky venture.’
    • ‘Dr. Dimitrov and Polis's team mined the data of three previous clinical trials that tested a variety of antiretrovirals in HIV-infected adults and children.’
    • ‘Prescriptions were written for a variety of antiretrovirals, antibiotics, antidepressants, and appetite enhancers.’
    • ‘One of the strategies adopted consists in utilizing combinations of fixed doses of generic antiretrovirals, involving three medicinal drugs of two different classes in the same tablet.’
    • ‘Numerous studies in HIV-infected women and children to determine appropriate doses of antiretrovirals and other drugs in these populations.’
    • ‘Medical staff interested in prescribing antiretrovirals were sent on training courses in Durban.’
    • ‘Second, those on triple therapy may have been on second-line treatment regimens or been on their current regimen for many months and therefore may already have been resistant to some antiretrovirals.’
    • ‘We need dedicated adolescent services to minimise loss to follow up, encourage adherence to treatment with antiretrovirals and prevent transmission of drug resistant virus.’
    • ‘Due to major reduction in prices of antiretrovirals, these drugs are now available in many countries.’
    • ‘The production process is far more complicated than that of other antiretrovirals, making the wholesale cost of the drug approximately $20,000 per patient per year.’
    • ‘Generic drug manufacturers in countries such as India are already ahead in the race to produce triple fixed dose antiretrovirals, because they can copy patented drugs produced by different companies and combine them.’