Definition of alkylation in English:



  • See alkylate

    • ‘Small alterations to bases, including oxidation and alkylation, are mainly repaired by the pathway known as base excision repair.’
    • ‘Important synthetic methodology also exists for the alkylation of enolate ions.’
    • ‘Likewise the mustard nitrogen of chlorambucil should not be covalently joined to antibody, since it must be free to generate the toxic aziridinium ion responsible for DNA alkylation.’
    • ‘These reactions occur via acylation or alkylation and are often rapid, forming stable primary amide or secondary amine bonds.’
    • ‘The same sample was resolved into 7 distinct spots by acrylamide alkylation.’