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Physiology. Originally (in experimental studies of muscle contraction): a load added to a strip of muscle after contraction has begun. In later use also: the force that a ventricle of the heart must generate in order to eject blood (determined largely by vascular resistance).
with object Physiology. To subject (a muscle) to an afterload.
with object Medicine. In radiotherapy: to load (a previously implanted receptacle) with a radioactive substance; to insert (a radioactive substance) into such a receptacle.
Mid 19th century (in an earlier sense). From after- + load<br>late 19th century; earliest use found in Brain: a journal of neurology. Probably partly from afterload, and partly from after- + load.
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