Definition of trypsinogen in English:



mass nounBiochemistry
  • An inactive substance secreted by the pancreas, from which the digestive enzyme trypsin is formed in the duodenum.

    • ‘As trypsinogen is secreted into the duodenum, it is changed into trypsin by enterokinase.’
    • ‘Examples of important proenzymes include pepsinogen, trypsinogen and chymotrypsinogen, which give rise to the proteolytic digestive enzymes.’
    • ‘Hypercalcemia increases calcium, which is believed to activate trypsinogen.’
    • ‘Trypsin also activates trypsinogen as well as all the other proenzymes in the pancreatic secretion, producing the active proteases and peptidases that hydrolyze dietary polypeptides.’
    • ‘Mesotrypsinogen comprises a minor portion of the total trypsinogen protein in the pancreas.’